Dr. Isreb is graduate of Damascus University school of Medicine. He finished his Internal medicine residency at St. Joseph hospital- Northern Univ. in Chicago and did his fellowship in Nephrology from Loyola University Medical Center in Chicago.
He has been in private practice since 2003. He has been active in medical relief through SAMS nephrology subcommittee and organized and led several medical missions to Jordan. He was the chairman of the Jordan relief committee and the chairman and the acting executive director of SAMS Foundation. Currently, he serves on its board of directors.